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KMID : 0352119920080020110
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Journal of Kyung Hee University
1992 Volume.8 No. 2 p.110 ~ p.114
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The Effect of Pretreatment with Small Dose of Succinylcholine on Potassium Level during Induction of Anesthesia
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Abstract
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Althought it has many disadvantages, sch is commonly used for endotracheal intubation. Intravenous administration of sch in normal adults increase potassium of serum up to 24%. With acute upper motor neuron lesion, spinal cord injury and massive
trauma,
serious and fatal hyperkalemia occur.
In this study, small dose of sch was pretreated during induction of anesthesia and observed its effect on serum potassium level. We studied 40 patients, ASA class physical status I-II, undergoing elective surgery and divided into two groups
randomly.
Group I: 0.2 mg/kg of sch pretreated before 1 mg/kg of sch administration.
Group II:0.5 ml of saline pretreated before 1 mg/kg of sch administration
Serum potassium level was checked before induction and every 1, 3, 5, and 7 minutes following sch administration.
@ES The results are as follows.
@EN 1) In the control group, the serum potassium level is significantly increased 3 mins after administration of sch, and slightly decreased 5 and 7 mins after administration of sch as compared with value at 3 mins. The mean potassium level is
increased
as compared with the control level.
2) In the experimental group, pretreated with sch, the serum potassium level is decreased 3 mins, 5 mins and 7 mins after administration of sch as compared to the control level. The mean serum potassium level is significantly decreased (p<0.05).
3) When pretreated with sch, the serum potassium level in the experimental group is significantly decreased as compared to the control group
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KEYWORD
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